Online,

Boston,

MA,

US,

ZIP: 02203

Phone: +4402031418700

From Cell Signaling to the Tumor Microenvironment, Exploit TGF-β’s Role in IO to Harness a Clinically Relevant, Safe & Efficacious Therapeutics

It is clear the world of TGF-β contains vast potential and excitement, in the past year alone we have seen great advances, clinical setbacks, and novel insights into the role of TGF-β.

Over the last 12 months, we have seen so many highs and lows, including clinical updates from large pharma such as Novartis, Oncotelic Therapeutics, Sanofi. It is also exciting to see emerging biotechs progressing in this area – from Transcenta’s clearance with the FDA for Ph1 anti-PD-L1/TGFb antibody to Lassen Therapeutics uncloaking $31m for their candidate.

With the vast volume of candidates moving into the clinic, it is vital for this community to reconnect at the 2nd TGF-β for Immuno-Oncology Drug Development Summit, the definitive industry-led meeting to harness the therapeutic potential of this target and supercharge pipeline progression.

Tailored with 31+ senior leaders, the 2022 meeting will return with a fresh speaker line-up and dedicated 2 tracks content for a comprehensive guide on TGF-β in immuno-oncology. Whether you are new to this field or a seasoned expert, this meeting will provide you with the must-know takeaways from biology to translational modeling, from biomarkers to clinical trial design across 3 days.

What’s New in 2022?
- Improve our core understanding of TGF-β function and biology
- With insights from Genentech, Leucid Bio, NIH and more, this summit will provide a comprehensive guide on the basic science of TGF-β
- Better mechanistic knowledge of TGF-β regulators
- Leverage insights into the interplay of cells in the tumor landscape and explore the methods for targeting TGF-β with Mestag Therapeutics, Takeda, and Kalivir Immunotherapeutics
- Gain novel insights into TGF-β and therapeutic interactions through advanced modeling
- Revolutionize preclinical insights with a new TGF-β reporter mouse from Lalage Wakefield and dive into current preclinical studies with Morphic and Synthis
- Elevate translation to avoid high toxicity profiles
- Examine PK/PD modeling to provide insights into toxicity and avoid clinical setbacks with iOnctura
- Layout a clear biomarker and patient selection strategy
- Develop a comprehensive biomarker strategy with Scholar Rock and explore the impact of patient selection to drive the greatest advantages for patients
- Understand past journeys and clinical setbacks to drive future success
- Explore the lessons learned from Novartis’ journey with TGF-β and understand the history of TGF-β in oncology – including lessons from the clinical experience of galunisertib

Tickets    https://go.evvnt.com/913463-1?pid=1052
Brochure https://go.evvnt.com/913463-3?pid=1052

Category: Conferences | Science, Health & Medicine | Pharmaceuticals | Drug Development

Prices:
Conference + Boot Camp Day - Drug Developer Pricing USD 2898.00
Conference Only - Drug Developer Pricing USD 2299.00
Boot Camp Day Only - Drug Developer Pricing USD 699.00
Conference + Boot Camp Day - Academic Pricing USD 2598.00
Conference Only - Academic Pricing USD 2099.00
Boot Camp Day Only - Academic Pricing USD 599.00
Conference + Boot Camp Day - Service Provider Pricing USD 3598.00
Conference Only - Service Provider Pricing USD 2899.00

Shannon Turley Vice President, Cancer Immunology Genentech, Lalage Wakefield Senior Investigator NIH, Michael Lahn Chief Medical Officer iOnctura, Chantal Kuhn Principal Scientist Takeda Oncology, Marc Pelletier Translational Immuno-Oncology Novartis, David Schaer Director - Translational Oncology Lead Pfizer, Si Tuen Lee-Hoeflich Director, Translational Sciences Scholar Rock, Alessandra Castiglioni Principle Scientific Researcher Genentech, Rachel Salazar Vice President, Head of Programs & Portfolio Bicara Therapeutics, Divya Mathur Director, Immuno-Oncology Regeneron Pharmaceuticals, Anthony Maida Chief Clinical Officer Oncotelic Inc, Zoe Johnson Chief Scientific Officer iOnctura, Anish Suri President & Chief Scientific Officer Cue Bio, Steve Thorne Chief Scientific Officer Kalivir Immunotherapuetics, John Maher Chief Scientific Officer Leucid Bio, Dori Thomas-Karyat Chief Executive Officer Synthis, Natalia Blanco Principle Scientist Morphic Therapeutics, James Legg Senior Vice President – Research & Early Development Mestag Therapeutics, Ravi Kumar Senior Vice President & Chief Scientific Officer Acceleron Pharma, Stephen Nishimura Professor & Chief of Pathology University of California San Francisco, Michael Shi Chief Medical Officer Transcenta, Wanjun Chen Senior Investigator & Chief, Mucosal Immunology NIH, Yuti Chernajovsky Emeritus Professor of Molecular Medicine Queen Mary University of London, Mark Travis Head of Division of Infection, Immunity & Respiratory Medicine University of Manchester, Davide Melisi Associate Professor of Medical Oncology University of Verona, Mary Helen Barcellos- Hoff Professor of Radiation Oncology University of California San Francisco, Julius Strauss Co-Director Laboratory of Tumor Immunology & Biology Center of Cancer Research, NCI, NIH, John Armstrong Managing Director - Biotech Outcome Capital, Nina Noskovicova Research Scientist Maxwell Therapeutics, Solomon Slim Lead Research Analyst Beacon Cytokine, Viviana Volta Senior Scientist Synthis